[Canna]

Ubiquinol supplements have been available for about four years and ubiquinone for forty. Very few studies have been completed on ubiquinol other than those conducted by Kaneko, the manufacturer. In fact, most of the information on the internet about ubiquinol is provided by Kaneko or its sellers. The UCSD researchers used ubiquinone and got the results which has us all taking 1200 mg of CoQ10 every day. Doses of up to 2400 mg are being tested. I understand the relationship between the two substances e.g., that it is harder for older bodies to break down ubiquinone, that there is much more ubiquinol in the body, etc. However, can we really assume that ubiquinol can be substituted for ubiquinone for our purposes when no study has been done to compare their efficacies in PD? Also, no dosage or dosage equivalency has been established for ubiquinol and everyone is really just guessing since we really don't know.

[Canna]

PS That said, shouldn't everyone be taking the 1200 mg of Vitamin E the UCSD subjects were given along with ubiquinone? Can we assume there was no important interaction between the two or was it for solubility only? Vitamin E alone has not been found to slow PD progression but don't we have to say that it was Vitamin E 1200 mg in combination with CoQ1O 1200 mg that slowed progression. Why is the focus on CoQ10 alone?