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Adverse effects of aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and clinical status in rhinovirus-infected volunteers....

http://www.ncbi.nlm.nih.gov/pubmed/2172402

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Effect of antipyretic therapy on the duration of illness in experimental influenza A,

http://www.ncbi.nlm.nih.gov/pubmed/11130213

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http://www.answers.com/+antipyretic+...0.651&method=3

From paint to pain: Friedrich Bayer and Friedrich Weskott were two buddies who set up an international paint and dye company in Germany in 1863. Scientists in 1886 discovered an antipyretic painkiller could be manufactured from the waste of one of the dye products. So, in 1888, the pair set up a pharmaceutical department." — Marilyn Linton; Little Pill Made a Big Difference; The Toronto Sun (Canada); Mar 14, 1999.

Antipyretics (literally "against the fire") are drugs that reduce fever.[1] They will not normally lower body temperature if one does not have a fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.

Most antipyretic medications have other purposes. The most common antipyretics in the United States are ibuprofen and aspirin, which are used primarily as pain relievers. Non-steroidal anti-inflammatory drugs (NSAIDs) are antipyretic, anti-inflammatory, and pain relievers. There is some debate over the appropriate use of such medications: fever is part of the body's immune response to infection.

The effectiveness of acetaminophen (paracetamol) as an antipyretic in children is unknown.[2]

Behaviors
Bathing or sponging with lukewarm or cool water can effectively reduce body temperature