Parkinson's Disease Tulip


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Old 06-26-2007, 05:02 PM #1
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Default Theory du jour - "Flatness"

Try this one on for size and see if it fits. And keep in mind there may be gender differences.

First, two established points. 1) PWP have "flattened" cortisol output graphs with the net result being an elevated level over the course of 24 hours. Normal folks have a "ski jump" graph that spikes sharply at daybreak and drops through the day in a characteristic graph. PWP, however, have an "ice rink" shape - flat - with the level overall being higher. 2) When stress does drive the level up, the PP (Parkinson's Poop) hits the fan as we know too well.

The above can be interpreted in a couple of ways. The usual one seems to be that we lack something. But there is another that the more I think about it the more it fits me, at least. What if our bodies know exactly what they are doing and intentionally keep cortisol within a flat zone for the excellent reason that we are hypersensitive to the hormone itself? Certain minimum levels are necessary for health so the system can't be shut down completely, but it can't be allowed to spike or we take damage.

It isn't that we are stodgy, dull, and dependable. It's that we sitting on a tank of nitroglycerin and trying to avoid the bumps. I know that I have always, and for no apparent reason, had a feeling that if I ever "lost it" there'd be hell to pay. Some unconscious recognition. But I'm the kind of guy that stops and helps turtles cross the road, even twenty pound snappers that their own mama would be cautious of! There is no logical reason for that feeling but I keep my emotions in tight check. At least the destructive ones. Passion, si! Anger, no! I hadn't thought about that until now. Hmmm.

Just musing.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 06-27-2007, 05:04 AM #2
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You could have a point there, Rick! I don't remember having been really angry in all my life prior to PD. I have always passionately engaged in just causes, was class speaker most of my school life, union leader at work, but I was never able to "actively dislike" anybody, even if they tried their best.
It was a very surprising new experience for me when, a few years into PD, I flew into a rage and cussed out a driver who had left his car double-parked beside mine and I had to wait several minutes for him to show up, before I could leave. He was truly stunned at my ferocity and I was absolutely disgusted with myself afterwards.

I'm sure that guy hasn't doubleparked again since then!
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Old 06-27-2007, 04:15 PM #3
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Default First and foremost...

...I do not - repeat - do not want to hurt anyone's feelings. But for the sake of this forum I have to point out that this is the way threads become "ot" enough to be called hijacked. I am sure that CTL has no such intention and, once again, I do not mean this to be personal or hurtful. I almost didn't reply at all, but I really do feel that this forum is disintegrating somewhat and feel obligated to speak up one last time. Maybe it doesn't matter to most but there was a time...
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 06-27-2007, 05:12 PM #4
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Question I was actually trying to help you?

Quote:
Originally Posted by reverett123 View Post
...I do not - repeat - do not want to hurt anyone's feelings. But for the sake of this forum I have to point out that this is the way threads become "ot" enough to be called hijacked. I am sure that CTL has no such intention and, once again, I do not mean this to be personal or hurtful. I almost didn't reply at all, but I really do feel that this forum is disintegrating somewhat and feel obligated to speak up one last time. Maybe it doesn't matter to most but there was a time...

hey reverett?
I couldn't for the life of me figure out what you may or may not have been implying?
actually I was trying to help you make an actual point ~
so I have to go to post another thread -
I am done with a "D" - done with rules...
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pd documentary - part 2 and 3

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Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these.
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