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Old 07-31-2008, 06:05 PM #1
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Default Tysabri

There have been 2 new cases of PML.

http://www.marketwatch.com/news/stor...3EED44821F8%7D
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Old 07-31-2008, 06:40 PM #2
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Wow Snoopy, this has only barely hit the wires.

Hopefully it's not true.

Cherie
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Old 07-31-2008, 06:46 PM #3
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Scary. My MS Specialist wanted to switch me from Betaseron, because it wasn't effective. She gave me several options, including Copaxone, Tysabri, and some research studies.

I chose Copaxone. Glad I didn't plan to go the Tysabri route.

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Old 07-31-2008, 06:47 PM #4
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I know it's only 2 cases in many thousands of Ty users, and yet it still is a worry.

You've been warned, so, now, it's a chance you choose to take....Be careful out there..

Thanks, Snoops.
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Old 07-31-2008, 07:33 PM #5
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Quote:
Originally Posted by SallyC View Post
I know it's only 2 cases in many thousands of Ty users, and yet it still is a worry.
Does anyone have confirmation on how many people are on Tysabri?

I got this 2-yr birthday announcement from the MSF earlier today, stating that close to 18,000 people were on it:

http://www.msfocus.org/online_newsDetails.php?ID=213

Other articles I read say "Tysabri was being used on more than 31,800 patients":

http://www.marketwatch.com/News/Stor...675091FAB73%7D

Cherie
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Old 07-31-2008, 07:59 PM #6
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Quote:
Originally Posted by lady_express_44 View Post
Does anyone have confirmation on how many people are on Tysabri?

I got this 2-yr birthday announcement from the MSF earlier today, stating that close to 18,000 people were on it:

http://www.msfocus.org/online_newsDetails.php?ID=213

Other articles I read say "Tysabri was being used on more than 31,800 patients":

http://www.marketwatch.com/News/Stor...675091FAB73%7D

Cherie
Their stock lost 85% of it's value in ONE day!!! I am concerned..
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Old 07-31-2008, 08:40 PM #7
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Quote:
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Their stock lost 85% of it's value in ONE day!!! I am concerned..
So far, everything I've read says:

"Shares of Biogen fell $12.26, or 17.6 percent, to $57.49 in after-hours trading."

"Shares of Elan fell $7.60, or 37.9 percent, to $12.45."

Something to be concerned about though, which is a new consideration for users:

"The three 2005 cases (of PML) involved patients who were simultaneously taking another MS-fighting drug; such combined therapy has been banned since 2005.

The patients in the most recent case had a history of taking other MS drugs but had been on Tysabri alone for at least 14 months, according to the SEC filing."

(From what I've read, one patient was on Tysabri for 17 months, and the other for 14 months.)

http://biz.yahoo.com/ap/080731/bioge...drug.html?.v=3

Even though Biogen has been forthright about the potential for new cases of PML to occur (no one can sue ), there was always the thought that the first cases occurred because the people had used Avonex as a combination therapy and/or the patient (Crohn's) had been on very strong immunosuppressants previously. So far, it doesn't sound like these two people were using anything else (except maybe steroids, which have not been considered a problem with Tysabri).

Biogen Idec and Elan Corporation, plc Host Conference Call For Investment Community, Scheduled to start Fri, Aug 1, 2008, 8:30 am Eastern:

http://biz.yahoo.com/cc/9/96099.html

Cherie
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Last edited by lady_express_44; 07-31-2008 at 08:52 PM. Reason: fix link, hopefully
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Old 07-31-2008, 08:47 PM #8
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Hi Cherie, your first link was a dead end. Can you cut and paste? Thanks.
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Old 07-31-2008, 08:50 PM #9
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I wonder if they're using the TOUCH program in Europe? I think that's where it happened. I wonder if these two could have been taking other immune suppressant drugs?

This is so sad. I hope they were able to get it out of their systems quickly enough to avoid too much damage.
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Old 07-31-2008, 08:51 PM #10
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Quote:
Originally Posted by Natalie8 View Post
Hi Cherie, your first link was a dead end. Can you cut and paste? Thanks.
This one?

http://hosted.ap.org/dynamic/stories...DEC_ELAN_DRUG?

or this one?

http://www.msfocus.org/online_newsDetails.php?ID=213

They all seem to work for me.
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