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09-15-2008, 05:48 PM
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CABASER(R) (Cabergoline) Product Information Update
11 Sep 2008 http://www.medilexicon.com/medicalne...?newsid=121031 Pfizer Australia is due to release new safety updates to the Cabaser® (cabergoline) Product Information which will come into effect on November 1, 2008. Ongoing review of clinical studies suggests that fibrosis and valvulopathy are associated with ergot-derived dopamine agonists, including Cabaser (cabergoline) and could be linked to cumulative doses of the medicine. Product Physician, Dr Louise Canny explained that as a result of these studies Pfizer Australia has decided to reduce the maximum daily dose of Cabaser (cabergoline) from 6mg per day to 3 mg per day. "It is anticipated that the reduction in the recommended maximum daily dose of Cabaser along with the current recommendations for assessment of patients prior to commencing therapy and during maintenance therapy included in the Cabaser Product Information, should help reduce the risk of fibrotic reactions," explained Dr Canny. READ article
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Australia: CABASER(R) (Cabergoline) Product Information Update
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