[Stitcher]

Alzheimer's, Parkinson's Diseases Could Be Halted By Protecting Neurons

16 Nov 2008
http://www.medicalnewstoday.com/articles/129412.php

Researchers at Southern Methodist University (SMU) and The University of Texas at Dallas (UTD) have identified a group of chemical compounds that slow the degeneration of neurons, a condition behind old-age diseases like Alzheimer's, Parkinson's and amyotrophic lateral sclerosis (ALS).

Their findings are featured in the November 2008 edition of Experimental Biology and Medicine. SMU Chemistry Professor Edward R. Biehl and UTD Biology Professor Santosh D'Mello teamed to test 45 chemical compounds. Four were found to be the most potent protectors of neurons, the cells that are core components of the human brain, spinal cord and peripheral nerves.

The most common cause of neurodegenerative disease is aging. Current medications only alleviate the symptoms but do not affect the underlying cause - degeneration of neurons. The identification of compounds that inhibit neuronal death is of urgent and critical importance.

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[jeanb]

Of course something that protects our neurons would be great. But what are their models for testing? CEP-1347 protected neurons in rats & monkeys but failed in human trials.

[ashleyk]

Hi, Below is the Pub Med article on this. Open "Full Text" to read all of paper. It's not easy to understand but it looks like the way to go to stop PD progression.

http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract