[iconophile]

MedScape.com defines rasagiline as a "...selective, irreversable inhibitor of MAO-B that is not metabolized into amphetamine dirivatives and has been shown to have neuroprotective..." blah-blah-blah.

My neuro wants to put me on Azilect but I've resisted compliance so far, with the excuse of needing to do more research.

Can anybody on the forum accurately interpret what that definiton actually means?


Thx,

John

[paula_w]

It means it is an improved version of eldepryl, which had some dietary restrictions, and turned into speed. You didn't mention how long you've had pd so i'm not sure what you may or may not know about eldepryl. [selegiline]

They claim that azilect is neuroprotective - which means it could slow down the progression of your illness. i have to add here that the claim of being neuroprotective is a great marketing plus and the research is not that convincing - it takes long term observation to prove that.I take a small dose of azilect and notice better mental clarity. I need all the mental clarity I can get.

can someone else add more? do you have to go off of azilect before surgery like you did with selegiline?

hope that helped
paula

Originally Posted by iconophile

MedScape.com defines rasagiline as a "...selective, irreversable inhibitor of MAO-B that is not metabolized into amphetamine dirivatives and has been shown to have neuroprotective..." blah-blah-blah.

My neuro wants to put me on Azilect but I've resisted compliance so far, with the excuse of needing to do more research.

Can anybody on the forum accurately interpret what that definiton actually means?


Thx,

John

[jeanb]

You do have to go off azilect for 2 weeks before surgery - and it's good to carry a card on you stating you are on an mao-b inhibitor.

You don't have to worry about the dietary restrictions that selegilene requires.

Agree with Paula about the claim for neuroprotection - many researchers don't think the evidence is there.