Taking meds once in the morning around 8 and again at night around 8. No on and off, no waiting for the meds to take effect. My right hand has slight tremor in certain positions but while at rest no tremor and while working no tremor heavily influenced. Changed Flexerill to one daily, half in morning and half in evening. My meds I am taking are:

1) Motrin 800mg 2 times daily
2) Flexeril 10mg 1/2 in am, 1/2 at night
3) Prozac 1 time daily
4) Cogentin 1mg 2 times daily

My overall feeling based upon what I have lost and gained by stopping the Sinemet is happiness subdued a bit by the possibility that the symptoms may come back or even possibly come back and worsen. But happiness from NO ON AND OFF time, the relief of taking pills every 30 minutes, from the muscle tightness, no need to favor left over right, ease of driving, ease of walking, and all related things; I have been overwhelmed with these results!

Here are the positives:

Absolutely no tight muscles
No problem driving
Meds taken at 8 am and 8 pm
No ON/OFF time
No problem eating although swallowing is sometimes a chore
No problem sleeping
90% of the time I walk normal and type normal
85% of the time no shaking of the hand/foot

Here are the negatives:

Drowsiness
Slight worsening memory loss
Possibly minor vision issues
Soft voice
Dry mouth-Very dry!
Some slowing down of movements
Still have difficulty accomplishing minor tasks-Apathy.

Please be advised as has been stated throughout this site: Seek the advice of a doctor before changing meds.

Thank you for allowing me to share this.

Jim