I have not heard of anything that prevents spread. However...I have heard of people who were able to get areas of spread to go into remission or the symptoms to lessen significantly by aggressively treating those areas at the first sign on spread (with the sorts of treatments that we all wish we could have gotten with an early diagnosis that most of us never get). Things like desensitization, physical therapy, lidocaine creams or patches, blocks, etc. That's not MY experience...but I have no reason to doubt those who have told me their first hand experience with it.