I still think Tecfidera will be a welcome new drug for some people. I have 2 pharmacist friends who really like the drug and are happy it has hit the market.

Remember the PML was in 1 or 2 cases over a 30 year span treating psoriasis. Tasabri is very much liked by many MSers, but it has a risk with it also.

For those who can not take the interferons, this may be their answer.
I felt much more energetic while on the Tecfidera and shortly after stopping it. Now I am feeling a bit crappy again and will be starting Avonex tomorrow. I still believe the Tecfidera perked me up a bit.

All these drugs are scary because it is a crap shoot as stated. Its a very personal decision between the patient and doctor on what to try.
I did fine on the interferon for 11 years but was very sick and tired of the shots and my skin was so sore all the time. So I tried the Tecfidera and I think if they would titrate it up more slowly, maybe I could have tolerated it. Not sure....will never know....but I'm glad I gave it a go.
I guess only time will tell how the general MS population really does on the Tecfidera.
For me personally, I am not ready to dismiss the medication. All medication carry risks. You have to be your own advacate.

Wish me luck with the Avonex!