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Old 08-10-2013, 09:23 PM
Bogusia Bogusia is offline
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Join Date: May 2013
Location: Vancouver Is
Posts: 90
10 yr Member
Bogusia Bogusia is offline
Junior Member
 
Join Date: May 2013
Location: Vancouver Is
Posts: 90
10 yr Member
Default Dyskinesia Tips

Quote:
Originally Posted by Jim091866 View Post
I ssem to be having lots of end of dose dyskinesia. My carbidopa doseage has been reasonably stable. Anyone found anything that works for this problem. I seem to recall amantadine? Thanks.
Few dyskinesia treatment tips some of them already mentioned by Rick.

"If you have severe dyskinesia(s) here are a few treatment tips we have found valuable over the years:

Go to a Parkinson’s specialist who has a lot of experience dealing with this issue, and remember it may take multiple visits to resolve the issue.
Remember that dyskinesia is usually driven by the dose of levodopa (sinemet) and/or agonist. Reducing the dose, and possibly taking smaller doses more frequently may be an option.
Remember that drugs like Entacapone (Comtan) (which is also a component of Stalevo) can make dyskinesia worse.
In severe cases, holding a dose or two of sinemet can be helpful to gain control of the situation. Remember stopping sinemet for a day or two can be dangerous so always consult your doctor for prolonged drug holidays (which are not recommended).
In severe prolonged and disabling dyskinesia many experts will eliminate dopamine agonists, MAO-B drugs, Comtan (or Stalevo), and may switch to a sinemet only regimen. They will search for a low dose of sinemet that will allow the patient to feel “on” with minimal to no dyskinesia. They will then give this low dose frequently enough to keep them “on” for as many hours in the day as possible.
Occasionally, patients with severe dyskinesia can be switched to liquid sinemet, although for most patients this is not a long-term viable strategy.
Amantadine can be added to a regimen to suppress dyskinesia– for some sufferers.
The most severe and medication resistant cases may be considered to be screened for deep brain stimulation or a duodopa pump.

Parkinson’s Treatment Tips is a blog brought to you by Dr. Michael S. Okun of the University of Florida Center for Movement Disorders and Neurorestoration"
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"Thanks for this!" says:
reverett123 (08-10-2013)