I had these as a child and they recently came back at 38. Genetic test confirmed a CACNA1A C to G transversion recently. Here's what has helped. Verapamil made me sick but stopped the headaches cold. Acetizolamide helped with fatigue and weakness to a point. I'm now off everything. Tight diet is a MUST. Only whole veggies, fruits, whole grains, natural meats, egg whites (I'm off nuts, beans, gluten, citrus, hydrolyzed proteins/MSG, dairy). All junk/processed food and binge eating/lots of carbs sets me off. Flights set me off. Moderate exercise, especially HIT cardio and weights, is GREAT. Long/slow cardio sets me off. NO alcohol. Light caffeine. Solid sleep. Butterbur, Magnesium may help. Daily breaks, routine and meditation help. Good luck! Read EVERYTHING on the internet. Lots of great info. You WILL fight through this.