Mestinon only lasts for me about 3 hours. I did find for myself that mestinon made me feel better but that I could not do any more. Just like you I would do too much and then have to crash in the recliner for hours, sometimes days. I finally learned that even though mestinon made me feel better, I still had to pace myself.

Mestinon does not cure the symptoms, it only temporarily improves them. For me, it gives me about a 20% boost. If try to behave like pre-MG me, I will pay for it with time in the recliner.

I know it is hard but if you pace yourself more, you will have less of the mestinon highs and lows.

kathie