Hi MSIndependent! Welcome to NT!

I have not taken Avonex so I can't give you any advise in regards to it. I know others on here use Avonex and will be able to give you advise.

I was on C for a few years and as time went on I had more and more of the horrible IPIRs. I went off of it and am currently not on any DMD, just managing symptoms with medications.

I'm not sure about the new orals. I've heard good and bad. There is a current thread on here started by KittyLady regarding Tecfidera. I think there is also another thread regarding Tecfidera that is a positive thread. Reading both of them might be helpful to you.

Good luck tomorrow and let us know how it goes.