I have not taken Wellbutrin so I don't have any advice regarding that drug specifically. However, the 1st AD type drug they tried me on was Cymbalta. I had a lot of nerve pain and the dr decided to try it as it works well for nerve pain in those with peripheral neuropathy. It worked fantastic for the nerve pain but for the 3 days I was on it I had aggressive thoughts and couldn't sleep. Like you, I was agitated also. I stopped taking it and called my PCP and said I wasn't going to take it anymore. It was not a good experience for me as I am not one to have those kinds of thoughts and it was pretty upsetting to me. The thoughts were so dark. Maybe talk to your dr about switching to something else if the side effects are too much for you to deal with.