What you describe definitely sounds like fatigue.
One thing that no one can see or understand, but will rob you of everything.
I have heard that amantedine (sp?) helps with fatigue.
I tried Nuvigil in '10 and resulted in a resting heart rate of 143 beats per minute. AND I STILL FELT EXHAUSTED
But everyone does react differently with the drugs. Your PCP should be able to prescribe one for you.
I find that yoga does KINDA help with fatigue. It seems it only helps for about 20 minutes afterwards, then I am back to bed mode.
I'm sorry you're having troubles with no answers behind them. Lots of people have debilitating symptoms with zero lesion activity in the CNS.
It's crazy how this disease differs from one to another
When you're feeling like you're dragging, lay thy body down and rest!