Ed, in most cases the treatment is for life. But it has raised my quality of life already, in just over three weeks, that it is well worth it! There is one documented case (that I'm having trouble finding a link for right now) of a teenager whose pituitary gland completely failed after a concussion that they supplemented all his hormones for five years, beginning them about one year after the concussion, and then his pituitary started working again spontaneously! But it's very rare after NED lasts over a year - like I said, his is the only case that I'm aware of. (I'm a layman - there may be others, but they aren't readily found.)