you might want to search the "ask the doctor" and ask the pharmacist websites
http://forum.parkinson.org/index.php...sk-the-doctor/
http://forum.parkinson.org/index.php...-neupro-patch/
i think both stated an opinion that if you can't tolerate mirapex, you won't tolerate neupo, another agonist. but ya never know.
azilect is supposed to extend on time in advanced pd.
i'm just taking C/L and no experience with neupro. azilect made me worse?(stopped after 2 days of .5mg) and have never tried comtan.