Last time I checked (a few years ago) Topiramate was FDA approved for tx of migraines. I can't stand the med as it causes big time memory issues for me, BUT no doubt it has helped with the frequency of my migraines. It is also now very very rare for me to need the Imitrx shot, which I had to take previously rather often. Now, I take Treximet as an abortive, which has the same ingredient as Imitrex (moderate dosage) and an analgesic. Anyway, Topamax might be something to discuss with your doctor.

I know some people have had some good luck with Botox. Even the ones I know who have gotten some relief, it's been somewhat confusing. I hope your second round of injections works better for you.

I have found keeping my Topamax dosage low, a relatively happy compromise.
I also more and more watch my food intake and have learned better and better ways to manage my stress.

Wishing you well...migraines are a special kind of heartache...but perhaps a special kind of lesson. After almost two decades of this...I'm trying to look at it this way,...not easy.