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Old 09-15-2013, 03:47 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

I really think you should discuss with your doctor, changing to another medication (not a diuretic) if you really need one.

Gone are the days, when diuretics were considered first line in mild hypertension.

This family of drugs is highly problematic, for long term use and may be causing some of your difficulties. They cause gout, depletion of magnesium and potassium, drug induced lupus.
Also because of the disulfide bonds, it has allergic potential.
Some people cannot handle disulfide containing drugs. They cause itching/rash which can be serious in some.

In fact a movement now in medicine is to not treat mild hypertension at all:
http://www.peoplespharmacy.com/2012/...lood-pressure/
Quote:
"Antihypertensive drugs used in the treatment of adults (primary prevention) with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg) have not been shown to reduce mortality or morbidity in RCTs [randomized controlled trials]. Treatment caused 9% of patients to discontinue treatment due to adverse effects. More RCTs are needed in this prevalent population to know whether the benefits of treatment exceed the harms."
This is only one site with this content. I read similar claims in a recent Smithsonian magazine edition.

There is more detail here in this article:
http://ajcn.nutrition.org/content/85/1/6.full
Most of the data collected was on D2 50,000 (1250micrograms) units (the typical RX version).
Quote:
The absence of adverse effects in clinical trials that used intakes up to 1250 μg vitamin D/d and the lack of adverse effects at lower doses inspires a high level of confidence in the data from the strongly designed clinical trials that used 250 μg vitamin D/d.
1000IU D is 25micrograms-- which is a very small amount.
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