I do not take any of those meds, so I can't comment on them changing things. But yes, symptoms definitely can change over time! I have had RSD/CRPS for over 22 years now. I first developed it in my face and had all the classic symptoms. I was treated aggressively and went into remission. When I came out of remission I did not have all of those symptoms, but I did have the pain and swelling! I hurt my right hand in 2009 and developed it there; I now have it throughout most of my body. I do not have as much discoloring and sensitivity as I used to. I have two spinal cord stimulators implanted for pain, I think them and time is what changed things for me.

So sorry you are dealing with this!
Nanc