Hi draggin´
PE is a physical process (blood filtering) which should be effective within a couple of days. However it only removes circulating antibodies (circulating within the plasma), there are also fixed antibodies which of course are not removed.
It depends also on the effectiveness of the other medications you are taking since the production of antibodies is not reduced by the PE process, only the built-up is reduced.
I have now one PE every two months which means the my rate of antibody generation is low and that PE adequately controls my AB level.
Maurice.