As far as exercise and having CMT, we cannot overdo it or CMT will exacerbate. When you feel pain or even pins and needles while walking or standing, even swimming, etc. it is enough. Exercise will help the healthy muscles but not the ones affected by CMT. Sometimes it may be hard to figure out. Different for even people who have CMT. No pain no gain is not for a CMTer. Just thought I'd throw this out there.