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ex-Member
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Join Date: Sep 2006
Posts: 110
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ex-Member
Join Date: Sep 2006
Posts: 110
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Jello wrestling in the sand
The primary problem in Parkinson's Disease is insufficient dopamine. Stress can at most exploit low dopamine levels by exacerbating symptoms. However, it can not in itself reduce dopamine levels in the dopaminergic neurons.
This can be verified by checking the enzyme studies for the two enzymes involved in dopamine formation (tyrosine 3-monooxygenase and L-aromatic amno acid decarboxylase). Their activity has been found not to be regulated by stress via adrenaline levels.
The intereraction between acteylcholine and dopamine regulating muscle contraction certainly isn't history. It's biochemical fact. That is why the major drug types for Parkinson's Disease are based on this fact by being either dopaminergic or anti-cholinergic.
If you ask most people whether they had stress during their childhood they will say yes. Those with Parkinson's, Alzheimer's, Epilepsy, Diabetes, the Common Cold, just about anyone. That doesn't mean that stress causes them.
For a sceintific theory to be correct, it must be consistent with the facts. Stress causing Parkinson's Disease simply doesn't do that. Stress at most can merely exacerbate Parkinson's Disease symptoms when Parkinson's Disease already exists.
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