I've been thinking about this situation you are facing, Karen.

What medications are you taking? All of them... and what do
you use for migraine, or migraine prophylaxis?

The triptans will interact with SSRI drugs. They can cause serotonin syndrome in some people.

When trying to get a handle on paresthesias, and/or PN it is helpful too look at your lifestyle.

1) if something irritates you, stop doing it for a while. Several months. This pertains to exercise, like running. Running is difficult to stop, because people become habituated to the runner's high. This this an increase of endogenous pain blocking neurotransmitters, called endorphins. When one first reducing running or stops, there might be rebound pain-- from pain generators that were always there, but blocked by the running.

2) I'd stop the wine and alcohol for 6months and see what happens. Congeners in wine, and sulfites, are irritating to some people, as well as the alcohol. If you have crossed a threshold with the wine, the alcohol will block pain briefly, and then wear off. Confusing the issues.
You want to be able to identify any pain generating areas in order to work on them.

3) Vaccines can be problematic. It will be up to you to decide what to do about them.

4) keep in mind, that menopause is coming, and this can mess with your nerves as the hormones change.

You can PM me your drug list if you prefer privacy, so I can look them up for you. Include all OTC and RX drugs, herbs etc.