I find the idea of rationing medication to the point that it falls just beneath some arbitrary threshold to be a bit insane. Don't let them do it to you. It is true that polypharmacy (multiple drugs loaded with interactions) can become a bear real quick. But if I tum up my sinemet to 1800 mg from 1600 mg to maintain my QOL, well God bless my pointy little head! Its not a though they have good research telling me that the Devil waits up there at the 2500 mg milepost. The truth is that they know even less than we do! So why do we put up with such foolishness?

I am currently taking, every two hours, a 10/100 sinemet plus a 20/200 CR sinemet. It works out to about eight or nine doses or 2400 mg or so but I am entitled to adjust the CR to reflect the fact that there is roughly a loss of about 25 mg to the matrix used. So, let's say that I am taking net ((200 x 8) less (25 x 8) + (100 x 8) or a total of 800 mg of the "baby" ones plus plus a total of 1600 mg of the "big" ones all of which comes to 2400 mg before I subtract the eight 25 mg credits for the "big" ones (or 200 mg for the little pile that you shaved off earlier)