Prednisone works on inflammation. Having too much inflammation can be a sign that you are depleted in Omega-3 fats...which are used by the body to repair nerve damage and reduce inflammation.

The 3 vitamins that work with it are, B12, B6 and folate.
If you are low in either of these 4 things, you cannot repair yourself and will have increased inflammatory responses.

Eating alot of carbs and sugar will also do this, as it pushes insulin up and insulin works on fatty acid chemistry to create more inflammatory peptides in the Cox-2 family.

You can get a good anti-inflammatory response by controlling your diet and taking the proper nutrients you may be missing.
Then you might not need any prednisone.

Prednisone really disrupts other nutrients as well:
This link shows all the upset Prednisone can cause:
http://www.chiro.org/nutrition/ABSTR...steroids.shtml

(besides raising your blood sugar, suppressing your immune system and making infections more likely.)

More on other drugs here:
http://www.chiro.org/nutrition/ABSTR...orticosteroids

Not all drugs have been studied, so things like Lyrica/gabapentin do not yet appear on these lists.
I own the reference that was the source for the website I am linking to.