My neuro/MDS and I have worked out a carbi/levo regimen of one each of regular 25/100 and 50/200CR first thing in the AM, repeated at 3.5-4 hr intervals throughout the day. This gives me a resonably fast start and seems to provide a "floor" of meds level to keep me on during the day. I also take one 100mg amantadine with the first carbi/levo "hit".
I am fortunate to experience very little dyskinesia, so far, and have been taking carbi/levo since day one of my diagnosis in April of 2001.
I also still take 4mg of dextromethorphan every night, having begun in 2005. Progression continues, but at what seems a slow rate.
Robert
p.s. I should add that, in addtion to only slight dyskinesia, I have never had much tremor, and increasing carbi/levo as progression continues does not create problems for me. My neuro told me at my last checkup "you can't take too much (carbi/levo)".
R