Hi Susanne, Since you already have hand and finger problems, arms, etc. due to CMT (I believe you have said you do) then overusing them can exacerbate the problem; CMT in this case. Quilting, crocheting, knitting, using a keyboard, etc. for long periods of time, and sometimes it doesn't have to be a long time, is not good. Even non-CMTers can encounter the problem. A person needs to take a break.