Before getting this disorder I was a nice healthy 125# of muscle. In the 10 yrs since getting it I have gone down to 100# then back up. I usually stay at 114, and no its not muscle. I haven't had a good appetite in all this time except when I'm pregnant, and little one number 2 is my last. I do drink the Boost Plus everyday which gives me some nutrients but im just not hungry. Even without being on a treatment I just am not hungry. I'm Southern and for me to turn down food or only take a bite or 2 and then be done is not me. I love good food. Heck I've been using my son's little bowls because I eat just about the same as he does. I can go a week without the mention of food.