View Single Post
Old 12-01-2013, 11:41 AM
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

There are really over 100 causes of neuropathy....all different.

Mostly PN affects afferent nerves.... those going from the peripheral parts of the body back to the brain...

http://faculty.washington.edu/chudler/cv.html
This link explains the 4 main types of afferent fibers.

Efferent nerves go from the brain down the spinal cord, and then
mostly innervate muscles.

This link is about efferent nerves (mostly motor)..
http://faculty.washington.edu/chudler/cells.html

It helps to understand how the body works, and these two links are pretty easy to get the idea.

There are also inhibitory nerves, which prevent other nerves from firing. These use GABA as a rule. (this is not gabapentin).
When these fail, then control of motor functions escapes and there can be seizures or dystonia, or myoclonus etc.

This article explains how Benzodiazepines control myoclonus, but not long term.
http://www.ncbi.nlm.nih.gov/pubmed/2165012

If your myoclonus is getting worse...and you are on a Benzo drug... Klonopin or Valium, this may be due to tolerance issues to them. These drugs work well in the short term, but not in the long term, as tolerance develops and people need higher and higher doses.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
mrsD is offline   Reply With QuoteReply With Quote