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Old 12-03-2013, 06:09 PM
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mrsD mrsD is offline
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Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Spacing them is not likely to change anything. One needs to understand how PPIs work. They have to be absorbed, and travel all around your body in the bloodstream, and revisit the stomach that way. Then (usually hours later than taken), they affect the proton pumps in the cells that release acid.

In fact YOUR drug is designed with coatings on the contents to NOT dissolve in the stomach at all. It doesn't really start to be absorbed until it hits the intestines with the bicarb that is present in the pancreatic fluids which dissolve the coating on the beads inside the capsules. You can open one and see the little beads.
I have heard that some OTC versions now have a little coated pellet instead of beads. But Prilosec has/had beads which are enteric coated.

http://www.pharminfotech.co.nz/manua...meprazole.html

When you take your Prilosec daily, you reach a steady state, eventually where the cells of the stomach are constantly being affected by yesterday's dosing from the blood stream. So it doesn't really matter WHEN you take your copper supplement, because your stomach is always low in acid 24/7 around the clock.
I have made this product many times for hospital patients or those in nursing homes who require tubal feedings.
(We compound Prilosec to a liquid by dissolving in bicarb first.
So it will pass thru feeding tubes, etc.)

This illustrates a typical doctor misconception. There are many of these often, involving misunderstanding how how drugs work, are formulated, and a misunderstanding of steady state dynamics in drug delivery, and drug metabolism in the liver (especially not understood by most doctors)

IF... and this is a big IF...you only took Prilosec now and then...you could avoid the low acid periods it causes, by a couple of days, and then take the copper. But for those taking every day...you will always be low in acid, which will affect the copper absorption. You might decide to drink a Coke with your copper, or have orange juice. That MIGHT help with copper absorption.
But copper supplementation is not common...so data is lacking on it.
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