I drive myself both ways and always have but my first series of treatments was in the hospital. It will take several hours (especially for your first one) and your driver will either have to wait or come back later. As mentioned by limpy, some individuals have problems with their treatment, but if you hydrate a lot before you go and ask for pre-medications (usually benedryl and/or pain meds), you may be okay. I think I would have someone drive me the first time and see how it goes from there.

Good luck!