My understanding is this but I may be wrong.
If you are under medicare, medicare does not cover home infusion unless you are medically 'home bound'. It does cover infusion given at an infusion center or a hosipital. The largest part of the cost is for the drug itself. Medicare covers the drug under part B, the medical part instead of part D the drug part. If you are not under Medicare (or Medicaid) standard coverage rules may apply.