I have also been on just about every med in the book. I am hyper sensitive to most of the meds. I don't know why they have to make they so strong! All of them seem to have major negative physical effects on me. Has your doctor done any analysis on your thyroid levels? I mean, like looking not just at the TSH, but at the T4, T3 and T3 uptake levle? My doctor recently put me on T3 to help with my depression. I don't know if it works or not yet, but I wondered if you had been given a drug like Cytomel that is T3?