This sure has been a quiet thread for quite some time.

I've searched for and read threads that have any mention of Tecfidera, but it looks like nobody has talked about it in this particular thread. I know that most meds don't help with PPMS, but my doctor has suggested that I try Tecfidera anyway. What I'm wondering is: do we have evidence that it doesn't help PPMS, or do we just not have evidence that it does?

I also have an opportunity to get into the next phase of the MN-166 trial. Anybody care to share your opinion on whether or not this trial might be a good thing to try?

Last question: is there any indication that Ampyra has any effect on people with PPMS?