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Old 12-21-2013, 08:39 PM
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ElaineD ElaineD is offline
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Join Date: Nov 2013
Location: North Carolina
Posts: 293
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ElaineD ElaineD is offline
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Join Date: Nov 2013
Location: North Carolina
Posts: 293
10 yr Member
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OH, Kitt you did say' NOT an autoimmune disease'. I guess people must think that it is. I thought maybe you preferred it not to be thought of as autoimmune. Since some people discount autoimmune conditions for some reason.

Actually, some autoimmune conditions are also thought to have genetic links:

(from Wikipedia) Scientists such as H. McDevitt, G. Nepom, J. Bell and J. Todd have also provided strong evidence to suggest that certain MHC class II allotypes are strongly correlated with:
HLA DR2 is strongly positively correlated with Systemic Lupus Erythematosus, narcolepsy[7] and multiple sclerosis, and negatively correlated with DM Type

HLA DR3 is correlated strongly with Sjögren's syndrome, myasthenia gravis, SLE, and DM Type 1.

HLA DR4 is correlated with the genesis of rheumatoid arthritis, Type 1 diabetes mellitus, and pemphigus vulgarism.

I have Immune Deficiency (CVID) which may have a genetic connection (My immunologist is studying my 'brand' of immune deficiency, looking for a genetic connection).

I also have autoimmune conditions, mostly BECAUSE I have a deficient immune system. 25% of those with my immune deficiency (CVID) also have autoimmune conditions. So my immune system does NOT protect me from disease, but it attacks my body.

And finally I have Peripheral neuropathy, profound, which can be related to my autoimmune condition, but probably isn't. There isn't any direct correlation between Immune Deficiency and PN that I've seen. I also have severe Coronary artery disease and severe osteoarthritis....both caused by inflammation.

Inflammation is the bane of my existence. And the PN.

But I do think the methylprednisolone is stopping the inflammatory response from my last IVIG, since I haven't started one, and I usually do 48 hours after the IVIG.

YAY

Hugs, Elaine
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"Thanks for this!" says:
hopeful (12-23-2013)