i've tried it, didn't help at all. i didn't do it thru perlmutter, got my neuro to write an rx for all the equipment and got the glutathione from a compounding pharmacy, had a nurse friend start the "push" IV and i administered it.
university of s. florida did a clinical study showing it was no more effective than placebo.
http://www.ncbi.nlm.nih.gov/pubmed/19230029
youtube videos have no policeman validating them. pharmacies can make a fortune selling IV glutathione, insurance doesn't pay for it. are those videos phonies? dont know, but there is a huge placebo affect with pd. give someone a 100mg sinemet tablet who has been OFF and they would look just the before and after in those videos. perlmutter is very convincing but if he had so much confidence in IV glutathione why hasn't he tried to get funding to do a study, hauser did.
as far as gluten goes, there are countries where wheat is a staple, such as egypt and other middle east countries, i don't see any higher incidence of neurological diseases in those countries.
perlmutter promotes perlmutter imho.
just my opinion. italians eat pasta everyday which is really high in gluten, higher than bread. my layman opinion is do what researchers recommend, follow the mediterranean diet. and do more than just accept whatever perlmutter says, research both sides. i can't believe PBS had him do a special which they use to raise funds.
bottom line, think about it, if IV glutathione really worked that well, we'd be doing it. you mention any supplement on this board and it gets researched on the internet. pd'ers pay $200 copays for azilect, they would shell out the money to pay for IV glutathione. the drug for the duodopa pump costs $65,000 or more/year. there is a tremendous market for any kind of pd treatment for advanced pd'ers no longer responding well to sinemet, there is money to do clinical trials for alternative treatments that you can't patent yet IV glutathione gets no attention except for perlmutter and i imagine some other docs. there are very wealthy pd'ers who would be using this if it works and plubicizing it if it did and there are none.
there is a researcher who did a study on nasal glutathione at bastyr university but hasn't published her results.
http://clinicaltrials.gov/show/NCT01398748