Yes, it is possible; and may be more common in patients who:

- are elderly (poor liver function, hyponatremia - low sodium levels & increased likelihood of falls)
- are taking some other medications
- have a history of liver disease/compromise (may take up to 3 times as long for the drug to clear)
- consume alcohol (liver disease)
- have kidney disorders
- have other medical conditions/disorders (digestive, kidney, cardio-vascular, diabetes, Central Nervous System)

Some of the more common, long term adverse reactions to Cymbalta seem to be related to poor liver clearance of the drug, which may allow it to accumulate over time.


For sure you should see your doctor.
It might be worth having your liver enzymes and function tested. Accumulation of the drug may be a cause of common side effects to appear after taking it for a period of time.

Cymbalta Official FDA information, side effects and uses.
http://www.drugs.com/pro/cymbalta.html

Hope that this helps and that you get it sorted out.

With love, Erika