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Old 01-08-2014, 12:02 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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HCTZ (hydrochlorothiazide) is on the list of drugs that may cause drug induced lupus.

There are many papers on PubMed mentioning it, but most don't have an abstract.

http://www.ncbi.nlm.nih.gov/pubmed/20693204
Quote:
Lupus. 2010 Aug;19(9):1107-11. doi: 10.1177/0961203310370349.
Drug-induced subacute cutaneous lupus erythematosus.
Callen JP.
Author information
Abstract

Subacute cutaneous lupus erythematosus (SCLE) is a subset of cutaneous lupus erythematosus with unique immunologic and clinical features. The first description dates back to 1985 when a series of five patients were found to have hydrochlorothiazide-induced SCLE. Since that time, at least 40 other drugs have been implicated in the induction of SCLE.

PMID:
20693204
[PubMed - indexed for MEDLINE]
It is also listed on this Medscape article in a list of drugs that will flare lupus:
http://emedicine.medscape.com/articl...#aw2aab6b2b3aa

This is a list of other adverse effects from HCTZ:
http://www.webmd.com/drugs/drug-5310...l&pagenumber=6
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