Hi Lottie! Thanks for the well wishes I think RSD/CRPS can spread to anywhere. I do not have RSD in my bladder, I have Interstitial Cystitis..which I read that it can be associated with RSD. Who knows!?! Dr thinks that it is RSD that is spreading to...umm...my lady parts. There are meds that they use specifically for IC, but I cannot take them. They also use a lot of the same meds for IC that they use for RSD and I cannot take any of them. I am gonna inquire about the suppositories that zookester mentioned to me.