It would be a great idea to just take a "MAGIC" Rx pill and lower our glutamate levels to save our axon/neurons. I do not think one exists.

There are numerous supplements that may do this job.

I have posted some of them and I will post more.

I would welcome any additional ones you folks can find.

jackD

Pflugers Arch. 2010 Jul;460(2):525-42. Epub 2010 Mar 14.

Glutamate receptors, neurotoxicity and neurodegeneration.

Lau A, Tymianski M.
SourceDivision of Applied and Interventional Research, Toronto Western Research Institute, 399 Bathurst Street, Toronto, ON, Canada, M5T 2S8.

Abstract
Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration.

As glutamate is a major excitatory neurotransmitter in the central nervous system (CNS), the implications of glutamate excitotoxicity are many and far-reaching.

Acute CNS insults such as ischaemia and traumatic brain injury have traditionally been the focus of excitotoxicity research.

However, glutamate excitotoxicity has also been linked to chronic neurodegenerative disorders such as amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease and others.

Despite the continued research into the mechanisms of excitotoxicity, there are currently no pharmacological interventions capable of providing significant neuroprotection in the clinical setting of brain ischaemia or injury.

This review addresses the current state of excitotoxic research, focusing on the structure and physiology of glutamate receptors; molecular mechanisms underlying excitotoxic cell death pathways and their interactions with each other; the evidence for glutamate excitotoxicity in acute neurologic diseases; laboratory and clinical attempts at modulating excitotoxicity; and emerging targets for excitotoxicity research.

PMID: 20229265 [PubMed - indexed for MEDLINE]