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Originally Posted by en bloc
Quick follow up question(s): Does Oxycontin or MS Contin contain acetaminophen?
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No. There is no acetaminophen in Oxycontin or MS Contin.
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If not, does the caffeine actually (noticeably) help for effectiveness, or more just to reduce the fatigue?
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Caffeine is a potentiator, but effectiveness depends on the individual and generally their sensitivity to caffeine.
There are many potentiators; aspirin, acetaminophen, ibuprofen, and caffeine are the common ones combined with pain medications. Other medications can act as potentiators as well, but that's best left between patient and doctor, as potentiators are basically medication interactions.
The deleterious effects of acetaminophen on the liver can be attenuated by taking
N-Acetyl Cysteine (NAC) along with the acetaminophen.
Oxycodone, the active ingredient in Percocet and Oxycontin, is
very effective on its own; it is ostensibly
1-1/2 times as potent as morphine taken orally, but that will depend on the individual.
Doc