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Old 01-17-2014, 08:40 AM
soccertese soccertese is offline
Magnate
 
Join Date: Nov 2007
Posts: 2,531
15 yr Member
soccertese soccertese is offline
Magnate
 
Join Date: Nov 2007
Posts: 2,531
15 yr Member
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Quote:
Originally Posted by aftermathman View Post
Is there an approximate dosage of ldopa when dysks start.

I am trying to keep below 800 mg per day and I do not suffer badly from them.

Neil.
everyone is different, i too try to stay under 800mg but go up to 900 at times.
i take combo of immediate release and controlled release sinemet, the 50/200 pill but count it as only 120mg in my calculations since assume 60% bioavailable. i'm cheating

only taking sinemet until recently,
i have added azilect which doesn't seem to make much difference, stopped it awhile back after a 3 week trial but decided to start it up again since wearing off is happening quicker. tried neupro patch samples up to 2mg, didn't notice any side affects or benefits but stopped since i can't rely on samples and can't afford the patch which would cost at least $450/month. if i could get it in canada it would be $250, checked with 2 canadians, it would sure be nice to just slap on a patch once a day and pop a few SINEMET CR's and not have to worry about missing a pill or protein interference which really decreases my l-dopa absorption.

i would have to assume a quick acting inhaled l-dopa would reduce the dyskinesias since you'd be able to take a lesser amount of oral l-dopa daily since you wouldn't have to be 100% ON all the time, you could use the inhaled l-dopa to "TOP OFF" assuming you could afford it. might be totally off base in that assumption.

have had dyskinesias only once, had to go to a party, IR sinemet wasn't kicking in, had taken a CR but didn't realize it was about to kick in, so took 100mg, that kicked in and then at the party the CR kicked in, that resulted in more mild swaying/bobbing than a lot of jerky motions.

I've read that 1200 might be considered high.
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