Hi, I was diagnosed about 3 years ago and my polyneuropathy started out wih the usual pain and burning...I worked in a commissary, so, lots of hrs in steel toe shoes on concrete floors, lots of lifting, pushing, pulling. Yikes! When I got to the point of "can't take the pain anymore" I went online and started reading. I had a problem with a flirtation with addiction to pain pills when I had a 4 month ear infection many years ago and I knew I couldn't go back there. I started reading about curcumin. Tried the formulations i could find but wasn't too impressed (they helped, but didn't do the trick). I studied the studies and learned that curcumin was one of the most studied substances and one of the safest and that it worked better for inflammation than steroids, which are the "gold standard" of treatment. Since inflammation was the cause of my pain, I was interested in this. Apparently, the problem with curcumin is it's not very absorbable by the body, only about 5%. If you take enough to get a good benefit, your intestines would not like it... One of the studies stated that a liposomal delivery system would be a way to get much better absorbtion, as much as 95%. I had just started making liposomal vitamin c, and had the equipment and ingredients, except curcumin, which was not easy to find, but find it I did. There was a recipe with curcumin, vitamin c and resvesterol on the internet and I just took the other ingredients out and tweaked the recipe until i got complete encapsulation. I was my own guinea pig and HERE IS THE AMAZING PART THAT WILL MAKE YOU WANT TO READ THIS POST...THE STUFF WORKS! NOT AS A PAIN RELIEVER, BUT AS AN INFLAMMATION REMOVER. WHEN I STOPPED TAKING IT ONCE, AFTER 11 DAYS THE PAIN STARTED COMING BACK! I HAVE NO INFLAMMATION, NEED NO PAIN MEDS, TAKE NO SUPPLEMENTS...JUST A ROOT (CURCUMIN), LECITHIN (KNOWN TESTED FOOD ADDITIVE, FROM SUNFLOWER) AND DISTILLED WATER. i HAVE GIVEN THIS TO MANY PEOPLE AND THE GREAT MAJORITY 85% HAVE THE SAME BENEFIT, ONE LADY GOT OFF OF OXYCONTIN AND, METHADONE WITHIN ONE WK OF STARTING THE CURCUMIN. a SMALL PERCENTAGE LESS THAN 10% HAVE CRAMPING, AND ABOUT 5% DON'T SEEM TO BENEFIT. THE ONLY OTHER SIDE EFFECTS ARE WEIGHT LOSS AND THE SCIENTISTS SAY THIS MAY EVEN BE THE SILVER BULLET TO PREVENT ALZHEIMERS. Anyone can make this incredible substance with less than $40 worth of equipment. If i can, i want to make it to sell one day soon.