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Old 02-02-2014, 04:57 AM
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Panorama Panorama is offline
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Panorama Panorama is offline
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Join Date: Jan 2014
Location: Silicon Valley
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Quote:
Originally Posted by scheshire1348 View Post
. . Prednisone okay, but I'm only on 30mg daily.
Samantha,

How long have you been on Prednisone? Here is the relevant chapter from the MG Manual:
The most predictable response to prednisone occurs when treatment begins with a dose of 1.5 to 2 mg/kg per day. This dose is given until sustained improvement occurs, which is usually within 2 weeks. The dose is then decreased over many months to the smallest amount necessary to maintain improvement, which is ideally less than 20 mg every other day. The rate of decrease should be individualized—patients who have a rapid initial response can reduce the dose on alternate days by 20 mg each month to 60 mg every other day. In those with a less dramatic initial response it may be preferable to change to an alternate day dose of 100 to 120 mg and taper this by 20 mg each month to 60 mg every other day. The dose is then tapered more slowly to a target dose of 10 mg every other day as long as improvement persists. If any weakness returns during dose reduction, the dose should be increased, another immunosuppressant should be added, or both, to prevent further worsening. Weakness invariably returns if the drug is stopped, but a very low dose (5 to 10 mg every other day) may be sufficient to maintain good improvement in many patients. For this reason, the dose is not reduced further than this unless another immunosuppressant is also being given. (MG Manual, page 19)
That sounds like a lot of Preds.

-Mark-

Last edited by Panorama; 02-02-2014 at 07:03 AM.
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