I have had periods of weight loss as well with this...since on IVIG I stabilized though.. but during exacerbations, I won't be able to swallow well, therefore can't eat, drink or take pills well.. I usually am super careful for a few days or week, then get my IVIG and then I'm good again! getting a cough or something where I Have to clear my throat often will wear down my throat quicker if I''m on the back end of my IVIG.. i have to rest and not clear my throat or cough if possible and will be better after 20 min or so.. fun stuff!