Quote:
Originally Posted by lurkingforacure
Badboy, I have read reports where, on autopsy of PWP, they did not find any alpha-synyclein clumps, yet the deceased had been dx'd with PD and been taking PD meds for years.....similarly, there are people who were never dx'd with PD who on autopsy, they found the clumps.
I have not found any research reconciling these conflicting findings.
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I've been invited to a presentation by Dr. Virginia Lee from the University of Penn, this Friday. She is one of the most renowned authorities in the world on the etiology and pathogenesis of alpha-synuclein, tau, and other misfolded disease proteins in the pathobiology of neurodegenerative diseases. She will be lecturing on the current state of the science regarding misfolded proteins and PD and AD. I will be happy to report back any interesting updates regarding a-syn and PD after the lecture.