 |
ex-Member
|
|
Join Date: Sep 2006
Posts: 110
|
|
|
ex-Member
Join Date: Sep 2006
Posts: 110
|
Monkeys
Quote:
Originally Posted by annefrobert
Furthermore, we have shown that new neurons are generated on a continuous basis in the striatum of normal adult monkeys
|
New neurons have long been known to be generated in adult humans, but not dopaminergic neurons. The dopaminergic neurons are just one of dozens of cell types in the brain.
There is irreversible loss of the dopaminergic neurons in adults. However, despite what is widely claimed it has never been shown there is anything more than minimal loss of dopaminergic neurons in most people with Parkinson's Disease. Cell loss isn't the problem.
There is considerable loss of cell activity of the dopaminergic neurons, not a considerable loss of the cells themselves.
The activity of the enzymes required for the formation of dopamine have consistently been shown to be low, with enzyme activity down to around 25% in milder cases, and down to 10% in severe cases.
Enzyme activity is changing continuously. It is not static or irreversible, which is one reason why Parkinson's Disease symptoms can vary throughout the day and from day to day.
Even the authors of the first research that falsely claimed that there was considerable cell loss in Parkinson's Disease asserted that any cell loss that existed could be fully compensated for by increasing the activity of the remaining cells.
|