Lexapro is on that list.
It is an SSRI (but does not have mixed neurotransmitter effects like the SNRIs...like Cymbalta or Effexor or Savella.)
It is a metabolite of Celexa --which had 2 racemic forms one of which was the active Lexapro. When Celexa's patent expired the company put Lexapro out. It is much more potent and active than the Celexa-- the latter is often given to serotonin sensitive people because it is much weaker.
The rationale for using antidepessants involves MIXED acting ones primarily. This is because the central (in the brain) pain loop reacts best to mixed types.
If you are overly sensitive to serotonin type drugs...then the obvious choice to me is using a
dopamine acting type. That
would be Wellbutrin (Bupropion). Starting with low doses and working up. Some people here have had success with this drug, and for men especially, it interferes with sexual activities the least.
I would bring this up with your doctor and here is a medical paper illustrating its usefulness with pain treatment:
http://www.ncbi.nlm.nih.gov/pubmed/18457535
Quote:
Expert Rev Neurother. 2008 May;8(5):781-97. doi: 10.1586/14737175.8.5.781.
Role of central dopamine in pain and analgesia.
Wood PB.
Author information
Abstract
Recent insights have demonstrated a central role for dopaminergic neurotransmission in modulating pain perception and natural analgesia within supraspinal regions, including the basal ganglia, insula, anterior cingulate cortex, thalamus and periaqueductal gray. In addition, while the participation of serotonin and norepinephrine in spinal descending inhibition of pain is well known, a critical role for dopamine in descending inhibition has also been demonstrated. Decreased levels of dopamine likely contribute to the painful symptoms that frequently occur in Parkinson's disease. Moreover, abnormalities in dopaminergic neurotransmission have been objectively demonstrated in painful clinical conditions, including burning mouth syndrome, fibromyalgia and restless legs syndrome. Evidence from animal models and indirect evidence from pharmaceutical trials also suggest a role for dopamine in chronic regional pain syndrome and painful diabetic neuropathy. Several novel classes of medication with analgesic properties have bearing on dopaminergic activity as evident in the capacity of dopamine antagonists to attenuate their analgesic capacity. An expanded appreciation for the role of dopamine in natural analgesia provides the impetus for further study involving preclinical models and advanced neuroimaging techniques in humans, which may lead to the development of novel therapeutic strategies.
PMID:
18457535
[PubMed - indexed for MEDLINE]
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